Publications
27) Janeen R. Jordan, Ernest E. Moore, Sagar S. Damle, Phillip Eckels, Jeffrey L. Johnson, Jonathan P. Roach, Jasmina S. Redzic, Kirk C. Hansen and Anirban Banerjee "Gelsolin is Depleted in Post-Shock Mesenteric Lymph" Journal of Surgical Research, 2007, Vol. 143, p130-135. pdf
26) McDermott RA, Porterfield HS, El Mezayen R, Burks AW, Pons L, Schlichting DG, Solomon B, Redzic J, Harbeck RJ, Duncan MW, Hansen KC, Dreskin SC. "Contribution of Ara h 2 to peanut-specific, IgE-mediated, cell activation." Clinical and Experimental Allergy, 2007, Vol. 37, p752. pdf
25) Zhongzhou Chen, Jianye Zang, John Kappler, Xia Hong, Frances Crawford, Qin Wang, Fei Lan, Chengyu Jiang, Johnathan Whetstine, Shaodong Dai, Kirk Hansen, Yang Shi, and Gongyi Zhang "Structural basis of the recognition of a methylated histone tail by JMJD2A" PNAS, 2007, 104, p10818-10823. pdf
24) Jan Hirsch, Kirk C. Hansen, Anil Sapru, James A. Frank, Robert J. Chalkley, Xiaohui Fang, Jonathan C. Trinidad, Peter Baker, Alma L. Burlingame and Michael A. Matthay "Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome" American Journal of Respiratory and Critical Care Medicine, 2007, Vol. 175, p 1006-1013. pdf
23) Zhongzhou Chen, Jianye Zang, Johnathan Whetstine, Xia Hong, Foteini Davrazou, Tatiana G. Kutateladze, Michael Simpson, Qilong Mao, Cheol-Ho Pan, Shaodong Dai, James Hagman, Kirk Hansen, Yang Shi, and Gongyi Zhang "Structural Insights into Histone Demethylation by JMJD2 Family Members" Cell, 2006, 125, 691-702. pdf
22) Jan Hirsch, Kirk C. Hansen, SooJinNa Choi, Joonhwa Noh, Ryutaro Hirose, John P. Roberts, Michael A. Matthay, Alma L. Bulingame, Jacquelyn J. Maher, and Claus U. Niemann "Warm ischemia induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats" Molecular & Cellular Proteomics, 2006, 5: 979-986. pdf
21) Fusheng Chen, Hiroshi Hasegawa, Gerold Schmitt-Ulms,Toshitaka Kawarai, Christopher Bohm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, Michael Glista , Ekaterina Rogaeva1, Yosuke Wakutani, Raphaelle Pardossi Piquard, Xueying Ruan, Anurag Tandon, Frederic Checler, Philippe Marambaud, Kirk Hansen, David Westaway, Peter St George-Hyslop, Paul Fraser "TMP21 Is A Presenilin Complex Component That Modulates g- But Not e-Secretase Activity" Nature, 2006, Vol 440, 1208-1212. pdf
20) Robert J. Chalkley, Kirk C. Hansen, Michael A. Baldwin, Biological Mass Spectrometry; Al Burlingame (Editor), "Bioinformatic Methods to Exploit Mass Spectrometric Data for Proteomic Applications" Book Chapter, Academic Press, January 2006, 289-311.
19) Robert J. Chalkley, Kirk C. Hansen, Michael A. Baldwin "Bioinformatic methods to exploit mass spectrometric data for proteomic applications" Methods in Enzymology, 2005, Vol. 402, p289-312. pdf
18) Robert J. Chalkley, Peter R. Baker, Lan Huang, Kirk C. Hansen, Nadia P. Allen, Michael Rexach, and A L. Burlingame "Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a QqTOF mass spectrometer: 2. New developments in protein prospector allow for reliable and comprehensive automatic analysis of large datasets" Molecular & Cellular Proteomics, 2005, 8, 1194. pdf
17) Robert J. Chalkley, Peter R. Baker, Kirk C. Hansen, Katalin F. Medzihradszky and A.L. Burlingame "Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a QqTOF mass spectrometer: 1. How much of the data is theoretically interpretable by search engines?" Molecular & Cellular Proteomics, 2005, 8, 1189. pdf
16) Sunney I. Chan, Joseph J.-T. Huang, Randy W. Larsen, Ronald S. Rock, and Kirk C. Hansen, Dynamic Studies in Biology: Phototriggers, Photoswitches and Caged Biomolecules; Maurice Goeldner (Editor), Richard Givens (Editor), "Early Kinetic Events in Protein Folding: The Development and Applications of Caged Peptides" Book Chapter, Wiley, April 2005, 479-494.
15) Masahiro Tanaka, Raynard Bateman, Daniel Rauh, Eugeni Vaisberg, Shyam Ramachandani, Chao Zhang, Kirk C. Hansen, Alma L. Burlingame, Kevan M. Shokat, and Cynthia L. Adams "An Unbiased Cell Morphology Based Screen for New Biologically Active Small Molecules" PLOS Biology 2005, Vol. 3, No. 5, e128. pdf comment
14) Keith Vosseller, Kirk C. Hansen, Robert J. Chalkley, Jonathan C. Trinidad, Lance Wells, Gerald W. Hart, Alma L. Burlingame "Quantitative analysis of both protein expression and serine / threonine post-translational modifications through stable isotope labeling with dithiothreitol" Proteomics 2005, Vol 5, No. 2, 388. pdf
13) Ronald S. Rock, Kirk C. Hansen, Randy W. Larsen and Sunney I. Chan "Rapid photochemical triggering of protein unfolding in a nondenaturing environment" Chemical Physics, 2004, Vol. 307, No. 2-3, 201. pdf
12) Pavel Strop, Alexander J. Bankovich, Kirk C. Hansen, K. Christopher Garcia and Axel T. Brunger "Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family." J. Mol. Biol. 2004, 343(4), 1055. pdf
11) Ana Serban, Giuseppe Legname, Kirk Hansen, Nadia Kovaleva, and Stanley B. Prusiner "Immunoglobulins in Urine of Hamsters with Scrapie" J. Biol. Chem. 2004, Vol. 279, No. 47, 48817. pdf
10) Christian F.W. Becker, Pavel Strop, Randal B. Bass, Kirk C. Hansen, Kaspar P. Locher, Gang Ren, Mark Yeager, Douglas C. Rees, and Gerd Kochendoerfer "Conversion of a Mechanosensitive Channel protein from a Membrane-embedded to a Water-soluble Form by Covalent Modification with Amphiphiles" J. Mol. Biol. 2004, 343(3), 747. pdf
9) Gerold Schmitt-Ulms, Kirk Hansen, Jialing Liu, Cynthia Cowdrey, Jian Yang, Stephen J. DeArmond, Fred E. Cohen, Stanley B. Prusiner and Michael A. Baldwin "Time controlled transcardiac perfusion crosslinking (tcTPC), a novel tool for the study of protein interactions in complex tissues" Nature Biotechnology, 2004, 22, 724. pdf
8) Pedro R. Cutillas Robert J. Chalkley, Kirk C. Hansen, Rainer Cramer, Anthony G. W. Norden, Mike D. Waterfield, Alma L. Burlingame, Robert J. Unwin "Abnormalities in the urinary proteome of Dent's disease patients (CLCN5 mutation) imply specificity in the reabsorption of proteins by renal proximal tubular cells" American Journal of Physiology-Renal Physiology 2004, May 12, 287. pdf
7) Jan Hirsch, Kirk C. Hansen, Alma L. Burlingame and Michael A. Matthay "Proteomics: Potential Applications to Lung Diseases" Invited Review: American Journal of Physiology-Lung, 2004, 287, L1. pdf
6) Kevan M. Shokat, Masahiro Tanaka, Al L. Burlingame, Chao Zhang, and Kirk C. Hansen "Novel Pyrazolo Pyrimidine Derivatives As Short Chain Dehydrogenases/Reductases Inhibitors" U.S. patent, March 2003.
5) J. Hirsch, K. C. Hansen J. A. Frank, X. Fang, R. J. Chalkley, A. L. Burlingame and M. A. Matthay "Changes in the proteome of alveolar type II epithelial cells after high tidal volume ventilation "Anasthesiologie und Intensivmedizin" November 2003, 44, 11.
4) Kirk C. Hansen, Gerold Schmitt-Ulms, Robert J. Chalkley, Jan Hirsch, Michael A. Baldwin, and A. L. Burlingame "Mass Spectrometric Analysis of Protein Mixtures at Low Levels Using Cleavable 13C-ICAT and Multi-Dimensional Chromatography" Molecular & Cellular Proteomics 2003, 5, 299. pdf
3) Kirk C. Hansen, Ronald S. Rock, Randy W. Larsen, and Sunney I. Chan. "A Method for Photoinitating Protein Folding", J. Am. Chem. Soc 2000, 122, 11567. pdf
2) Kirk C. Hansen, Brian E. Schultz, Guangyang Wang, Sunney I. Chan. "Reaction of Escherichia coli cytochrome bo3 and mitochondrial cytochrome bc1 with a photoreleasable decylubiquinol" Biochim. Biophys. Acta. 2000, 1456, 121. pdf
1) Brian E. Schultz, Kirk C. Hansen, Charles C. Lin, and Sunney I. Chan. " Rapid photochemical generation of ubiquinol through a radical pathway: an avenue for probing submillisecond enzyme kinetics" J. Org. Chem. 2000, 65, 3244. pdf